Targeting of copper-trafficking chaperones causes gene-specific systemic pathology in Drosophila melanogaster: prospective expansion of mutational landscapes that regulate tumor resistance to cisplatin

Copper, a transition metal, is an essential component for normal growth and development. It acts as a critical co-factor of many enzymes that play key roles in diverse cellular processes. The present study attempts to investigate the regulatory functions decisively controlling copper trafficking dur...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Theotoki, Eleni I., Velentzas, Athanassios D., Katarachia, Stamatia A., Papandreou, Nikos C., Kalavros, Nikolas I., Pasadaki, Sofia N., Giannopoulou, Aikaterini F., Giannios, Panagiotis, Iconomidou, Vassiliki A., Konstantakou, Eumorphia G., Anastasiadou, Ema, Papassideri, Issidora S., Stravopodis, Dimitrios J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826294/
https://ncbi.nlm.nih.gov/pubmed/31575544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.046961
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