Cyclin-dependent kinase 1-mediated AMPK phosphorylation regulates chromosome alignment and mitotic progression

AMP-activated protein kinase (AMPK), a heterotrimeric serine/threonine kinase and cellular metabolic sensor, has been found to regulate cell cycle checkpoints in cancer cells in response to energetic stress, to harmonize proliferation with energy availability. Despite AMPK's emergent associatio...

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Vydáno v:J Cell Sci
Hlavní autoři: Stauffer, Seth, Zeng, Yongji, Santos, Montserrat, Zhou, Jiuli, Chen, Yuanhong, Dong, Jixin
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826014/
https://ncbi.nlm.nih.gov/pubmed/31519809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.236000
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