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Cyclin-Dependent Kinase 1-Mediated Phosphorylation of YES Links Mitotic Arrest and Apoptosis during Antitubulin Chemotherapy

YES is a member of the SRC family kinase (SFK) group of non-receptor tyrosine kinases, which are implicated in multiple key cellular processes involved in oncogenesis. Antitubulin agents have been widely used as chemotherapeutics for cancer patients and these drugs arrest cells in mitosis, leading t...

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Опубликовано в: :Cell Signal
Главные авторы: Wang, Zhan, Chen, Xingcheng, Zhong, Mei-Zuo, Yang, Shuping, Zhou, Jiuli, Klinkebiel, David L, Karpf, Adam R, Chen, Yuanhong, Dong, Jixin
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170005/
https://ncbi.nlm.nih.gov/pubmed/30223016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2018.09.007
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