Macrophage‐specific hypoxia‐inducible factor‐1α deletion suppresses the development of liver tumors in high‐fat diet‐fed obese and diabetic mice

AIMS/INTRODUCTION: Chronic inflammation of the liver is often observed with obesity or type 2 diabetes. In these pathological conditions, the immunological cells, such as macrophages, play important roles in the development or growth of liver cancer. Recently, it was reported that hypoxia‐inducible...

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Pubblicato in:J Diabetes Investig
Autori principali: Takikawa, Akiko, Usui, Isao, Fujisaka, Shiho, Tsuneyama, Koichi, Okabe, Keisuke, Nakagawa, Takashi, Nawaz, Allah, Kado, Tomonobu, Jojima, Teruo, Aso, Yoshimasa, Hayakawa, Yoshihiro, Yagi, Kunikimi, Tobe, Kazuyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825928/
https://ncbi.nlm.nih.gov/pubmed/30897274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.13047
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