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LRRK2 N551K and R1398H variants are protective in Malays and Chinese in Malaysia: A case–control association study for Parkinson's disease

BACKGROUND: The LRRK2 gene is associated with Parkinson's disease (PD) as a number of mutations within the gene have been shown to be susceptibility factors. Studies on various global populations have determined that mutations such as G2019S, G2385R, and R1628P in LRRK2 increase the risk of dev...

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Detalhes bibliográficos
Publicado no:Mol Genet Genomic Med
Main Authors: Gopalai, Aroma Agape, Lim, Jia Lun, Li, Hui‐Hua, Zhao, Yi, Lim, Thien Thien, Eow, Gaik B., Puvanarajah, Santhi, Viswanathan, Shanthi, Norlinah, Mohamed Ibrahim, Abdul Aziz, Zariah, Lim, Soo Kun, Tan, Chong Tin, Tan, Ai Huey, Lim, Shen‐Yang, Tan, Eng‐King, Ahmad Annuar, Azlina
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825847/
https://ncbi.nlm.nih.gov/pubmed/31487119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.604
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