LRRK2 G2385R and R1628P Mutations Are Associated with an Increased Risk of Parkinson's Disease in the Malaysian Population

The LRRK2 gene has been associated with both familial and sporadic forms of Parkinson's disease (PD). The G2019S variant is commonly found in North African Arab and Caucasian PD patients, but this locus is monomorphic in Asians. The G2385R and R1628P variants are associated with a higher risk o...

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Detalhes bibliográficos
Main Authors: Gopalai, Aroma Agape, Lim, Shen-Yang, Chua, Jing Yi, Tey, Shelisa, Lim, Thien Thien, Mohamed Ibrahim, Norlinah, Tan, Ai Huey, Eow, Gaik Bee, Abdul Aziz, Zariah, Puvanarajah, Santhi Datuk, Viswanathan, Shanthi, Looi, Irene, Lim, Soo Kun, Tan, Li Ping, Chong, Yip Boon, Tan, Chong Tin, Zhao, Yi, Tan, E. K., Ahmad-Annuar, Azlina
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163406/
https://ncbi.nlm.nih.gov/pubmed/25243190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/867321
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