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LRRK2 N551K and R1398H variants are protective in Malays and Chinese in Malaysia: A case–control association study for Parkinson's disease

BACKGROUND: The LRRK2 gene is associated with Parkinson's disease (PD) as a number of mutations within the gene have been shown to be susceptibility factors. Studies on various global populations have determined that mutations such as G2019S, G2385R, and R1628P in LRRK2 increase the risk of dev...

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Dettagli Bibliografici
Pubblicato in:Mol Genet Genomic Med
Autori principali: Gopalai, Aroma Agape, Lim, Jia Lun, Li, Hui‐Hua, Zhao, Yi, Lim, Thien Thien, Eow, Gaik B., Puvanarajah, Santhi, Viswanathan, Shanthi, Norlinah, Mohamed Ibrahim, Abdul Aziz, Zariah, Lim, Soo Kun, Tan, Chong Tin, Tan, Ai Huey, Lim, Shen‐Yang, Tan, Eng‐King, Ahmad Annuar, Azlina
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825847/
https://ncbi.nlm.nih.gov/pubmed/31487119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.604
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