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miR- 26a Sensitizes Melanoma Cells To Dabrafenib Via Targeting HMGB1-Dependent Autophagy Pathways

BACKGROUND: Melanoma is known as the most aggressive and lethal type of cutaneous cancer due to its rapid development of drug resistance to chemotherapy drugs. METHODS: In our study, we conducted a variety of studies, including quantitative PCR, Western blot, and autophagy and apoptosis assays to in...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Yu, Yan, Xiang, Niu, Lin, Min, Huang, Jin-Wen, Zhang, Jing, Cheng, Bo, Ji, Chao
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825511/
https://ncbi.nlm.nih.gov/pubmed/31754297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S225671
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