miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy

The present study identified miR-638 as one of the most significantly overexpressed miRNAs in metastatic lesions of melanomas compared with primary melanomas. miR-638 enhanced the tumorigenic properties of melanoma cells in vitro and lung colonization in vivo. mRNA expression profiling identified ne...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bhattacharya, Animesh, Schmitz, Ulf, Raatz, Yvonne, Schönherr, Madeleine, Kottek, Tina, Schauer, Marianne, Franz, Sandra, Saalbach, Anja, Anderegg, Ulf, Wolkenhauer, Olaf, Schadendorf, Dirk, Simon, Jan C., Magin, Thomas, Vera, Julio, Kunz, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413631/
https://ncbi.nlm.nih.gov/pubmed/25650662
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