Mapping heterogeneity in patient-derived melanoma cultures by single-cell RNA-seq

Recent technological advances in single-cell genomics make it possible to analyze cellular heterogeneity of tumor samples. Here, we applied single-cell RNA-seq to measure the transcriptomes of 307 single cells cultured from three biopsies of three different patients with a BRAF/NRAS wild type, BRAF...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Gerber, Tobias, Willscher, Edith, Loeffler-Wirth, Henry, Hopp, Lydia, Schadendorf, Dirk, Schartl, Manfred, Anderegg, Ulf, Camp, Gray, Treutlein, Barbara, Binder, Hans, Kunz, Manfred
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2016
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352202/
https://ncbi.nlm.nih.gov/pubmed/27903987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13666
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