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Endoplasmic reticulum stress-induced autophagy determines the susceptibility of melanoma cells to dabrafenib
Melanoma is one of the deadliest skin cancers and accounts for most skin-related deaths due to strong resistance to chemotherapy drugs. In the present study, we investigated the mechanisms of dabrafenib-induced drug resistance in human melanoma cell lines A375 and MEL624. Our studies support that bo...
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| Publicado no: | Drug Des Devel Ther |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4977101/ https://ncbi.nlm.nih.gov/pubmed/27536070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S112740 |
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