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Characterizing the Role of HMG-CoA Reductase in Aryl Hydrocarbon Receptor-Mediated Liver Injury in C57BL/6 Mice

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor. The prototypical ligand of the AHR is an environmental contaminant called 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). TCDD exposure is associated with many adverse health outcomes in humans including non-alcoholic fatty...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dornbos, Peter, Jurgelewicz, Amanda, Fader, Kelly A., Williams, Kurt, Zacharewski, Timothy R., LaPres, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825130/
https://ncbi.nlm.nih.gov/pubmed/31676775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52001-2
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