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HISTONE DEACETYLASE 7 INHIBITION IN A MURINE MODEL OF GRAM-NEGATIVE PNEUMONIA-INDUCED ACUTE LUNG INJURY

BACKGROUND: Pulmonary infections remain the most common cause of Acute Respiratory Distress Syndrome (ARDS), a pulmonary inflammatory disease with high mortality, for which no targeted therapy currently exists. We have previously demonstrated an ameliorated syndrome with early, broad spectrum Histon...

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Detalhes bibliográficos
Publicado no:Shock
Main Authors: Kasotakis, George, Kintsurashvili, Ekaterina, Galvan, Manuel D., Graham, Christopher, Purves, J. Todd, Agarwal, Suresh, Corcoran, David L., Sullenger, Bruce A., Palmer, Scott M., Remick, Daniel G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824972/
https://ncbi.nlm.nih.gov/pubmed/31083049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000001372
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