Brain-specific Drp1 regulates postsynaptic endocytosis and dendrite formation independently of mitochondrial division

Dynamin-related protein 1 (Drp1) divides mitochondria as a mechano-chemical GTPase. However, the function of Drp1 beyond mitochondrial division is largely unknown. Multiple Drp1 isoforms are produced through mRNA splicing. One such isoform, Drp1(ABCD), contains all four alternative exons and is spec...

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Опубликовано в: :eLife
Главные авторы: Itoh, Kie, Murata, Daisuke, Kato, Takashi, Yamada, Tatsuya, Araki, Yoichi, Saito, Atsushi, Adachi, Yoshihiro, Igarashi, Atsushi, Li, Shuo, Pletnikov, Mikhail, Huganir, Richard L, Watanabe, Shigeki, Kamiya, Atsushi, Iijima, Miho, Sesaki, Hiromi
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2019
Предметы:
Cell Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824841/
https://ncbi.nlm.nih.gov/pubmed/31603426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44739
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