Brain-specific Drp1 regulates postsynaptic endocytosis and dendrite formation independently of mitochondrial division

Dynamin-related protein 1 (Drp1) divides mitochondria as a mechano-chemical GTPase. However, the function of Drp1 beyond mitochondrial division is largely unknown. Multiple Drp1 isoforms are produced through mRNA splicing. One such isoform, Drp1(ABCD), contains all four alternative exons and is spec...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Itoh, Kie, Murata, Daisuke, Kato, Takashi, Yamada, Tatsuya, Araki, Yoichi, Saito, Atsushi, Adachi, Yoshihiro, Igarashi, Atsushi, Li, Shuo, Pletnikov, Mikhail, Huganir, Richard L, Watanabe, Shigeki, Kamiya, Atsushi, Iijima, Miho, Sesaki, Hiromi
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2019
Sujets:
Cell Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824841/
https://ncbi.nlm.nih.gov/pubmed/31603426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44739
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