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Brain-specific Drp1 regulates postsynaptic endocytosis and dendrite formation independently of mitochondrial division

Dynamin-related protein 1 (Drp1) divides mitochondria as a mechano-chemical GTPase. However, the function of Drp1 beyond mitochondrial division is largely unknown. Multiple Drp1 isoforms are produced through mRNA splicing. One such isoform, Drp1(ABCD), contains all four alternative exons and is spec...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Itoh, Kie, Murata, Daisuke, Kato, Takashi, Yamada, Tatsuya, Araki, Yoichi, Saito, Atsushi, Adachi, Yoshihiro, Igarashi, Atsushi, Li, Shuo, Pletnikov, Mikhail, Huganir, Richard L, Watanabe, Shigeki, Kamiya, Atsushi, Iijima, Miho, Sesaki, Hiromi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824841/
https://ncbi.nlm.nih.gov/pubmed/31603426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44739
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