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Transforming Olefins into γ,δ-Unsaturated Nitriles by Cu-Catalysis

We developed a strategy to transform olefins into homoallylic nitriles by a mechanism that combines copper catalysis with alkyl nitrile radicals. The radicals are easily generated from alkyl nitriles in the presence of a mild oxidant, di-terf-butyl peroxide. This cross-dehydrogenative coupling betwe...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Wu, Xuesong, Riedel, Jan, Dong, Vy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824592/
https://ncbi.nlm.nih.gov/pubmed/28796438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201705859
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