Probing compartment-specific sphingolipids with targeted bacterial sphingomyelinases and ceramidases

Sphingolipids contribute to the regulation of cell and tissue homeostasis, and disorders of sphingolipid metabolism lead to diseases such as inflammation, stroke, diabetes, and cancer. Sphingolipid metabolic pathways involve an array of enzymes that reside in specific subcellular organelles, resulti...

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Bibliografiske detaljer
Udgivet i:J Lipid Res
Main Authors: Sakamoto, Wataru, Canals, Daniel, Salamone, Silvia, Allopenna, Janet, Clarke, Christopher J., Snider, Justin, Obeid, Lina M., Hannun, Yusuf A.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824496/
https://ncbi.nlm.nih.gov/pubmed/31243119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M094722
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