The Integrator complex cleaves nascent mRNAs to attenuate transcription

Cellular homeostasis requires transcriptional outputs to be coordinated, and many events post-transcription initiation can dictate the levels and functions of mature transcripts. To systematically identify regulators of inducible gene expression, we performed high-throughput RNAi screening of the Dr...

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Vydáno v:Genes Dev
Hlavní autoři: Tatomer, Deirdre C., Elrod, Nathan D., Liang, Dongming, Xiao, Mei-Sheng, Jiang, Jeffrey Z., Jonathan, Michael, Huang, Kai-Lieh, Wagner, Eric J., Cherry, Sara, Wilusz, Jeremy E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824465/
https://ncbi.nlm.nih.gov/pubmed/31530651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.330167.119
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