Planarians recruit piRNAs for mRNA turnover in adult stem cells

PIWI proteins utilize small RNAs called piRNAs to silence transposable elements, thereby protecting germline integrity. In planarian flatworms, PIWI proteins are essential for regeneration, which requires adult stem cells termed neoblasts. Here, we characterize planarian piRNAs and examine the roles...

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Detalles Bibliográficos
Publicado en:Genes Dev
Main Authors: Kim, Iana V., Duncan, Elizabeth M., Ross, Eric J., Gorbovytska, Vladyslava, Nowotarski, Stephanie H., Elliott, Sarah A., Sánchez Alvarado, Alejandro, Kuhn, Claus-D.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824462/
https://ncbi.nlm.nih.gov/pubmed/31537626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.322776.118
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