Planarians recruit piRNAs for mRNA turnover in adult stem cells

PIWI proteins utilize small RNAs called piRNAs to silence transposable elements, thereby protecting germline integrity. In planarian flatworms, PIWI proteins are essential for regeneration, which requires adult stem cells termed neoblasts. Here, we characterize planarian piRNAs and examine the roles...

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Détails bibliographiques
Publié dans:Genes Dev
Auteurs principaux: Kim, Iana V., Duncan, Elizabeth M., Ross, Eric J., Gorbovytska, Vladyslava, Nowotarski, Stephanie H., Elliott, Sarah A., Sánchez Alvarado, Alejandro, Kuhn, Claus-D.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2019
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824462/
https://ncbi.nlm.nih.gov/pubmed/31537626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.322776.118
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