Exenatide regulates pancreatic islet integrity and insulin sensitivity in the nonhuman primate baboon Papio hamadryas

The glucagon-like peptide-1 receptor agonist exenatide improves glycemic control by several and not completely understood mechanisms. Herein, we examined the effects of chronic intravenous exenatide infusion on insulin sensitivity, β cell and α cell function and relative volumes, and islet cell apop...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Fiorentino, Teresa Vanessa, Casiraghi, Francesca, Davalli, Alberto M., Finzi, Giovanna, La Rosa, Stefano, Higgins, Paul B., Abrahamian, Gregory A., Marando, Alessandro, Sessa, Fausto, Perego, Carla, Guardado-Mendoza, Rodolfo, Kamath, Subhash, Ricotti, Andrea, Fiorina, Paolo, Daniele, Giuseppe, Paez, Ana M., Andreozzi, Francesco, Bastarrachea, Raul A., Comuzzie, Anthony G., Gastaldelli, Amalia, Chavez, Alberto O., Di Cairano, Eliana S., Frost, Patrice, Luzi, Livio, Dick, Edward J., Halff, Glenn A., DeFronzo, Ralph A., Folli, Franco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824445/
https://ncbi.nlm.nih.gov/pubmed/31536476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93091
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