Exenatide regulates pancreatic islet integrity and insulin sensitivity in the nonhuman primate baboon Papio hamadryas

The glucagon-like peptide-1 receptor agonist exenatide improves glycemic control by several and not completely understood mechanisms. Herein, we examined the effects of chronic intravenous exenatide infusion on insulin sensitivity, β cell and α cell function and relative volumes, and islet cell apop...

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Détails bibliographiques
Publié dans:JCI Insight
Auteurs principaux: Fiorentino, Teresa Vanessa, Casiraghi, Francesca, Davalli, Alberto M., Finzi, Giovanna, La Rosa, Stefano, Higgins, Paul B., Abrahamian, Gregory A., Marando, Alessandro, Sessa, Fausto, Perego, Carla, Guardado-Mendoza, Rodolfo, Kamath, Subhash, Ricotti, Andrea, Fiorina, Paolo, Daniele, Giuseppe, Paez, Ana M., Andreozzi, Francesco, Bastarrachea, Raul A., Comuzzie, Anthony G., Gastaldelli, Amalia, Chavez, Alberto O., Di Cairano, Eliana S., Frost, Patrice, Luzi, Livio, Dick, Edward J., Halff, Glenn A., DeFronzo, Ralph A., Folli, Franco
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824445/
https://ncbi.nlm.nih.gov/pubmed/31536476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93091
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