CD83 orchestrates immunity toward self and non-self in dendritic cells

Dendritic cells (DCs) are crucial to balance protective immunity and autoimmune inflammatory processes. Expression of CD83 is a well-established marker for mature DCs, although its physiological role is still not completely understood. Using a DC-specific CD83–conditional KO (CD83(ΔDC)) mouse, we pr...

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Bibliografiska uppgifter
I publikationen:JCI Insight
Huvudupphovsmän: Wild, Andreas B., Krzyzak, Lena, Peckert, Katrin, Stich, Lena, Kuhnt, Christine, Butterhof, Alina, Seitz, Christine, Mattner, Jochen, Grüner, Niklas, Gänsbauer, Maximilian, Purtak, Martin, Soulat, Didier, Winkler, Thomas H., Nitschke, Lars, Zinser, Elisabeth, Steinkasserer, Alexander
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2019
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824307/
https://ncbi.nlm.nih.gov/pubmed/31527313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126246
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