CD83 orchestrates immunity toward self and non-self in dendritic cells

Dendritic cells (DCs) are crucial to balance protective immunity and autoimmune inflammatory processes. Expression of CD83 is a well-established marker for mature DCs, although its physiological role is still not completely understood. Using a DC-specific CD83–conditional KO (CD83(ΔDC)) mouse, we pr...

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Publicado en:JCI Insight
Main Authors: Wild, Andreas B., Krzyzak, Lena, Peckert, Katrin, Stich, Lena, Kuhnt, Christine, Butterhof, Alina, Seitz, Christine, Mattner, Jochen, Grüner, Niklas, Gänsbauer, Maximilian, Purtak, Martin, Soulat, Didier, Winkler, Thomas H., Nitschke, Lars, Zinser, Elisabeth, Steinkasserer, Alexander
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2019
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824307/
https://ncbi.nlm.nih.gov/pubmed/31527313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126246
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