CD83 orchestrates immunity toward self and non-self in dendritic cells

Dendritic cells (DCs) are crucial to balance protective immunity and autoimmune inflammatory processes. Expression of CD83 is a well-established marker for mature DCs, although its physiological role is still not completely understood. Using a DC-specific CD83–conditional KO (CD83(ΔDC)) mouse, we pr...

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Publicat a:JCI Insight
Autors principals: Wild, Andreas B., Krzyzak, Lena, Peckert, Katrin, Stich, Lena, Kuhnt, Christine, Butterhof, Alina, Seitz, Christine, Mattner, Jochen, Grüner, Niklas, Gänsbauer, Maximilian, Purtak, Martin, Soulat, Didier, Winkler, Thomas H., Nitschke, Lars, Zinser, Elisabeth, Steinkasserer, Alexander
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824307/
https://ncbi.nlm.nih.gov/pubmed/31527313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126246
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