CD83 orchestrates immunity toward self and non-self in dendritic cells

Dendritic cells (DCs) are crucial to balance protective immunity and autoimmune inflammatory processes. Expression of CD83 is a well-established marker for mature DCs, although its physiological role is still not completely understood. Using a DC-specific CD83–conditional KO (CD83(ΔDC)) mouse, we pr...

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Опубликовано в: :JCI Insight
Главные авторы: Wild, Andreas B., Krzyzak, Lena, Peckert, Katrin, Stich, Lena, Kuhnt, Christine, Butterhof, Alina, Seitz, Christine, Mattner, Jochen, Grüner, Niklas, Gänsbauer, Maximilian, Purtak, Martin, Soulat, Didier, Winkler, Thomas H., Nitschke, Lars, Zinser, Elisabeth, Steinkasserer, Alexander
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2019
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824307/
https://ncbi.nlm.nih.gov/pubmed/31527313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126246
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