ApoA-I Mimetic Peptide Reduces Vascular and White Matter Damage After Stroke in Type-2 Diabetic Mice

Diabetes leads to an elevated risk of stroke and worse functional outcome compared to the general population. We investigate whether L-4F, an economical ApoA-I mimetic peptide, reduces neurovascular and white-matter damage in db/db type-2 diabetic (T2DM) stroke mice. L-4F (16 mg/kg, subcutaneously a...

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Publicat a:Front Neurosci
Autors principals: Wang, Xiaohui, Li, Rongwen, Zacharek, Alex, Landschoot-Ward, Julie, Chopp, Michael, Chen, Jieli, Cui, Xu
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823666/
https://ncbi.nlm.nih.gov/pubmed/31708728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.01127
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