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Administration of Downstream ApoE Attenuates the Adverse Effect of Brain ABCA1 Deficiency on Stroke

The ATP-binding cassette transporter member A1 (ABCA1) and apolipoprotein E (ApoE) are major cholesterol transporters that play important roles in cholesterol homeostasis in the brain. Previous research demonstrated that specific deletion of brain-ABCA1 (ABCA1(−B/−B)) reduced brain grey matter (GM)...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Wang, Xiaohui, Li, Rongwen, Zacharek, Alex, Landschoot-Ward, Julie, Wang, Fengjie, Wu, Kuan-Han Hank, Chopp, Michael, Chen, Jieli, Cui, Xu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274914/
https://ncbi.nlm.nih.gov/pubmed/30373276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113368
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