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The ABCA1/ApoE/HDL pathway mediates GW3965-induced neurorestoration after stroke

BACKGROUND AND PURPOSE: ATP-binding cassette transporter A1 (ABCA1) is a major reverse cholesterol-transporter and plays critical role in the formation of brain high-density-lipoprotein (HDL) cholesterol. Apolipoprotein-E (ApoE) is the most abundant apolipoprotein and transports cholesterol into cel...

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Detalhes bibliográficos
Publicado no:Stroke
Main Authors: Cui, Xu, Chopp, Michael, Zhang, Zhenggang, Li, Rongwen, Zacharek, Alex, Landschoot-Ward, Julie, Venkat, Poornima, Chen, Jieli
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5263181/
https://ncbi.nlm.nih.gov/pubmed/28028143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.116.015592
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