MiR-126 mediates brain endothelial cell exosome treatment induced neurorestorative effects after stroke in T2DM mice

BACKGROUND AND PURPOSE: Stroke patients with type two diabetes mellitus (T2DM) exhibit increased vascular and white matter (WM) damage, and have worse prognosis compared to non-diabetic stroke patients. We investigated the neurorestorative effects of exosomes derived from mouse brain endothelial cel...

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Gepubliceerd in:Stroke
Hoofdauteurs: Venkat, Poornima, Cui, Chengcheng, Chopp, Michael, Zacharek, Alex, Wang, Fengjie, Landschoot-Ward, Julie, Shen, Yi, Chen, Jieli
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756941/
https://ncbi.nlm.nih.gov/pubmed/31394992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.119.025371
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