Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism

Pu-erh tea displays cholesterol-lowering properties, but the underlying mechanism has not been elucidated. Theabrownin is one of the most active and abundant pigments in Pu-erh tea. Here, we show that theabrownin alters the gut microbiota in mice and humans, predominantly suppressing microbes associ...

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Vydáno v:Nat Commun
Hlavní autoři: Huang, Fengjie, Zheng, Xiaojiao, Ma, Xiaohui, Jiang, Runqiu, Zhou, Wangyi, Zhou, Shuiping, Zhang, Yunjing, Lei, Sha, Wang, Shouli, Kuang, Junliang, Han, Xiaolong, Wei, Meilin, You, Yijun, Li, Mengci, Li, Yitao, Liang, Dandan, Liu, Jiajian, Chen, Tianlu, Yan, Chao, Wei, Runmin, Rajani, Cynthia, Shen, Chengxing, Xie, Guoxiang, Bian, Zhaoxiang, Li, Houkai, Zhao, Aihua, Jia, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823360/
https://ncbi.nlm.nih.gov/pubmed/31672964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12896-x
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