Gut microbiota-bile acid crosstalk contributes to the rebound weight gain after calorie restriction in mice

Caloric restriction is a common approach to weight reduction, however, weight regain is common. Here the authors report that caloric restriction reduces the abundance of Parabacteroides distasonis in the gut and alters serum bile acid (BA) profile, which contribute to weight regain in mice.

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Main Authors: Mengci Li, Shouli Wang, Yitao Li, Mingliang Zhao, Junliang Kuang, Dandan Liang, Jieyi Wang, Meilin Wei, Cynthia Rajani, Xinran Ma, Yajun Tang, Zhenxing Ren, Tianlu Chen, Aihua Zhao, Cheng Hu, Chengxing Shen, Weiping Jia, Ping Liu, Xiaojiao Zheng, Wei Jia
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Portfolio 2022-04-01
Sraith:Nature Communications
Rochtain Ar Líne:https://doi.org/10.1038/s41467-022-29589-7
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