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Specialized structural and functional roles of residues selectively conserved in subfamilies of the pleckstrin homology domain family

Homologous domains embedded in multidomain proteins of different domain architectures (DA) may exhibit subtle, but important, differences in their structure and function. Here, we consider two multidomain proteins, Arf nucleotide binding site opener (ARNO) and G protein‐coupled receptor kinase 2 (GR...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Naveenkumar, Nagarajan, Sowdhamini, Ramanathan, Srinivasan, Narayanaswamy
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823287/
https://ncbi.nlm.nih.gov/pubmed/31436855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12725
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