CUSP: an algorithm to distinguish structurally conserved and unconserved regions in protein domain alignments and its application in the study of large length variations

BACKGROUND: Distantly related proteins adopt and retain similar structural scaffolds despite length variations that could be as much as two-fold in some protein superfamilies. In this paper, we describe an analysis of indel regions that accommodate length variations amongst related proteins. We have...

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Hlavní autoři: Sandhya, Sankaran, Pankaj, Barah, Govind, Madabosse Kande, Offmann, Bernard, Srinivasan, Narayanaswamy, Sowdhamini, Ramanathan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423364/
https://ncbi.nlm.nih.gov/pubmed/18513436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-8-28
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