Hypoxia Induces Drug Resistance in Colorectal Cancer through the HIF-1α/miR-338-5p/IL-6 Feedback Loop

Hypoxia is associated with poor prognosis and therapeutic resistance in cancer patients. Accumulating evidence has shown that microRNA (miRNA) plays an important role in the acquired drug resistance in colorectal carcinoma (CRC). However, the role of miRNA in hypoxia-induced CRC drug resistance rema...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Xu, Ke, Zhan, Yueping, Yuan, Zeting, Qiu, Yanyan, Wang, Haijing, Fan, Guohua, Wang, Jie, Li, Wei, Cao, Yijun, Shen, Xian, Zhang, Jun, Liang, Xin, Yin, Peihao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822233/
https://ncbi.nlm.nih.gov/pubmed/31208913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.05.017
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