Hypoxia Induces Drug Resistance in Colorectal Cancer through the HIF-1α/miR-338-5p/IL-6 Feedback Loop

Hypoxia is associated with poor prognosis and therapeutic resistance in cancer patients. Accumulating evidence has shown that microRNA (miRNA) plays an important role in the acquired drug resistance in colorectal carcinoma (CRC). However, the role of miRNA in hypoxia-induced CRC drug resistance rema...

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Publicat a:Mol Ther
Autors principals: Xu, Ke, Zhan, Yueping, Yuan, Zeting, Qiu, Yanyan, Wang, Haijing, Fan, Guohua, Wang, Jie, Li, Wei, Cao, Yijun, Shen, Xian, Zhang, Jun, Liang, Xin, Yin, Peihao
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2019
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822233/
https://ncbi.nlm.nih.gov/pubmed/31208913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.05.017
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