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Widespread Changes in Positive Allosteric Modulation of the Muscarinic M(1) Receptor in Some Participants With Schizophrenia
BACKGROUND: Preclinical and some human data suggest allosteric modulation of the muscarinic M(1) receptor (CHRM1) is a promising approach for the treatment of schizophrenia. However, it is suggested there is a subgroup of participants with schizophrenia who have profound loss of cortical CHRM1 (MRDS...
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| Pubblicato in: | Int J Neuropsychopharmacol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6822142/ https://ncbi.nlm.nih.gov/pubmed/31428788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyz045 |
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