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Thermotolerance in the pathogen Cryptococcus neoformans is linked to antigen masking via mRNA decay-dependent reprogramming

A common feature shared by systemic fungal pathogens of environmental origin, such as Cryptococcus neoformans, is their ability to adapt to mammalian core body temperature. In C. neoformans, this adaptation is accompanied by Ccr4-mediated decay of ribosomal protein mRNAs. Here we use the related, bu...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Bloom, Amanda L. M., Jin, Richard M., Leipheimer, Jay, Bard, Jonathan E., Yergeau, Donald, Wohlfert, Elizabeth A., Panepinto, John C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821889/
https://ncbi.nlm.nih.gov/pubmed/31666517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12907-x
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