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Thermotolerance in the pathogen Cryptococcus neoformans is linked to antigen masking via mRNA decay-dependent reprogramming

A common feature shared by systemic fungal pathogens of environmental origin, such as Cryptococcus neoformans, is their ability to adapt to mammalian core body temperature. In C. neoformans, this adaptation is accompanied by Ccr4-mediated decay of ribosomal protein mRNAs. Here we use the related, bu...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Bloom, Amanda L. M., Jin, Richard M., Leipheimer, Jay, Bard, Jonathan E., Yergeau, Donald, Wohlfert, Elizabeth A., Panepinto, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821889/
https://ncbi.nlm.nih.gov/pubmed/31666517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12907-x
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