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Uncoupling of mRNA synthesis and degradation impairs adaptation to host-temperature in Cryptococcus neoformans

The pathogenic fungus Cryptococcus neoformans must overcome multiple stressors to cause disease in its human host. In this study, we report that C. neoformans rapidly and transiently repressed ribosomal protein (RP) transcripts during a transition from 30°C to host-temperature. This repression was a...

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Detalhes bibliográficos
Main Authors: Bloom, Amanda L. M., Solomons, J. T. Graham, Havel, Virginia E., Panepinto, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103160/
https://ncbi.nlm.nih.gov/pubmed/23659661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12258
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