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Uncoupling of mRNA synthesis and degradation impairs adaptation to host-temperature in Cryptococcus neoformans

The pathogenic fungus Cryptococcus neoformans must overcome multiple stressors to cause disease in its human host. In this study, we report that C. neoformans rapidly and transiently repressed ribosomal protein (RP) transcripts during a transition from 30°C to host-temperature. This repression was a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bloom, Amanda L. M., Solomons, J. T. Graham, Havel, Virginia E., Panepinto, John C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103160/
https://ncbi.nlm.nih.gov/pubmed/23659661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12258
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