Intracerebroventricular injection of ouabain causes mania-like behavior in mice through D2 receptor activation

Intracerebroventricular (ICV) administration of ouabain, an inhibitor of the Na, K-ATPase, is an approach used to study the physiological functions of the Na, K-ATPase and cardiotonic steroids in the central nervous system, known to cause mania-like hyperactivity in rats. We describe a mouse model o...

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Publicado no:Sci Rep
Main Authors: Lopachev, Alexander, Volnova, Anna, Evdokimenko, Anna, Abaimov, Denis, Timoshina, Yulia, Kazanskaya, Rogneda, Lopacheva, Olga, Deal, Alex, Budygin, Evgeny, Fedorova, Tatiana, Gainetdinov, Raul
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821712/
https://ncbi.nlm.nih.gov/pubmed/31666560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52058-z
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