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Cognitive flexibility impairment and reduced frontal cortex BDNF expression in the ouabain model of mania
Central infusion of the Na+/K+-ATPase inhibitor, ouabain in rats serves as an animal model of mania because it leads to hyperactivity, as well as reproduces ion dysregulation and reduced BDNF levels similar to that observed in bipolar disorder. Bipolar disorder is also associated with cognitive infl...
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| Publié dans: | Neuroscience |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5136525/ https://ncbi.nlm.nih.gov/pubmed/27267245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2016.05.058 |
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