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More Is Less: A Disinhibited Prefrontal Cortex Impairs Cognitive Flexibility
The prefrontal cortex (PFC) is critical for decision making, and it becomes dysfunctional in many neuropsychiatric disorders. Studies in schizophrenia patients and relevant animal models suggest loss of PFC inhibitory interneuron function. For instance, rats with a neonatal ventral hippocampal lesio...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3073623/ https://ncbi.nlm.nih.gov/pubmed/21159980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4623-10.2010 |
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