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More Is Less: A Disinhibited Prefrontal Cortex Impairs Cognitive Flexibility

The prefrontal cortex (PFC) is critical for decision making, and it becomes dysfunctional in many neuropsychiatric disorders. Studies in schizophrenia patients and relevant animal models suggest loss of PFC inhibitory interneuron function. For instance, rats with a neonatal ventral hippocampal lesio...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gruber, Aaron J., Calhoon, Gwendolyn G., Shusterman, Igor, Schoenbaum, Geoffrey, Roesch, Matthew R., O'Donnell, Patricio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073623/
https://ncbi.nlm.nih.gov/pubmed/21159980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4623-10.2010
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