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Acute Exacerbation of Sleep Apnea by Hyperoxia Impairs Cognitive Flexibility in Brown-Norway Rats

STUDY OBJECTIVES: To determine whether learning deficits occur during acute exacerbation of spontaneous sleep related breathing disorder (SRBD) in rats with high (Brown Norway; BN) and low (Zucker Lean; ZL) apnea propensity. DESIGN: Spatial acquisition (3 days) and reversal learning (3 days) in the...

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Detalhes bibliográficos
Main Authors: Topchiy, Irina, Amodeo, Dionisio A., Ragozzino, Michael E., Waxman, Jonathan, Radulovacki, Miodrag, Carley, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: Associated Professional Sleep Societies, LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196068/
https://ncbi.nlm.nih.gov/pubmed/25364080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.4184
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