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Role of Natural IgM and IgM induced Bregs in preventing ischemia induced innate inflammation and AKI
Ischemic AKI is predominantly mediated by the innate inflammatory response to DAMPS released during the reperfusion phase of the ischemic event. Here we show that pre-emptive IgM infusions to increase binding of natural IgM (nIgM) antibodies to leucocyte receptors (IgM-ALA), inhibit this inflammator...
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| Publicado en: | Nephron |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6821571/ https://ncbi.nlm.nih.gov/pubmed/31288230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000501639 |
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