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Natural IgM Anti-Leukocyte Auto-Antibodies (IgM-ALA) Attenuate Excess Inflammation Mediated by Innate and Adaptive Immune Mechanisms Involving TH-17

Little is known about the function of natural IgM auto-antibodies and especially IgM with anti-leukocyte reactivity (IgM-ALA). Natural IgM-ALA auto-antibodies are present at birth and characteristically increase during inflammatory and infective conditions. Our prior clinical observations and those...

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Detalhes bibliográficos
Main Authors: Lobo, Peter I., Bajwa, Amandeep, Schlegel, Kailo H., Vengal, John, Lee, Sang J., Huang, Liping, Ye, Hong, Deshmukh, Umesh, Wang, Tong, Pei, Hong, Okusa, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273570/
https://ncbi.nlm.nih.gov/pubmed/22262657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101762
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