HLA*LA—HLA typing from linearly projected graph alignments

SUMMARY: HLA*LA implements a new graph alignment model for human leukocyte antigen (HLA) type inference, based on the projection of linear alignments onto a variation graph. It enables accurate HLA type inference from whole-genome (99% accuracy) and whole-exome (93% accuracy) Illumina data; from lon...

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Foilsithe in:Bioinformatics
Main Authors: Dilthey, Alexander T, Mentzer, Alexander J, Carapito, Raphael, Cutland, Clare, Cereb, Nezih, Madhi, Shabir A, Rhie, Arang, Koren, Sergey, Bahram, Seiamak, McVean, Gil, Phillippy, Adam M
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2019
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Applications Notes
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821427/
https://ncbi.nlm.nih.gov/pubmed/30942877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz235
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