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Molecular basis of abasic site sensing in single-stranded DNA by the SRAP domain of E. coli yedK
HMCES and yedK were recently identified as sensors of abasic sites in ssDNA. In this study, we present multiple crystal structures captured in the apo-, nonspecific-substrate-binding, specific-substrate-binding, and product-binding states of yedK. In combination with biochemical data, we unveil the...
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| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6821365/ https://ncbi.nlm.nih.gov/pubmed/31504793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz744 |
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