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Ash2l interacts with Oct4-stemness circuitry to promote super-enhancer-driven pluripotency network
Pluripotency and cell fates can be modulated through the regulation of super-enhancers; however, the underlying mechanisms are unclear. Here, we showed a novel mechanism in which Ash2l directly binds to super-enhancers of several stemness genes to regulate pluripotency and self-renewal in pluripoten...
Zapisane w:
| Wydane w: | Nucleic Acids Res |
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| Główni autorzy: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6821267/ https://ncbi.nlm.nih.gov/pubmed/31555818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz801 |
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