Musashi-1 promotes cancer stem cell properties of glioblastoma cells via upregulation of YTHDF1

BACKGROUND: Glioblastoma (GBM) is the most lethal brain tumor characterized by high morbidity and limited treatment options. Tumor malignancy is usually associated with the epigenetic marks, which coordinate gene expression to ascertain relevant phenotypes. One of such marks is m6A modification of R...

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Veröffentlicht in:Cancer Cell Int
Hauptverfasser: Yarmishyn, Aliaksandr A., Yang, Yi-Ping, Lu, Kai-Hsi, Chen, Yi-Chen, Chien, Yueh, Chou, Shih-Jie, Tsai, Ping-Hsing, Ma, Hsin-I., Chien, Chian-Shiu, Chen, Ming-Teh, Wang, Mong-Lien
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734781/
https://ncbi.nlm.nih.gov/pubmed/33317545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01696-9
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